常見例句Here we introduced the clinical application development of NONMEM and analyzed recent ten years of typical internal and external documents. 本文通過對國內(nèi)外近十年來大量運用該法研究的論文進行歸納整理,介紹群體藥代動力學(xué)研究中非線性混合效應(yīng)模型法的臨床應(yīng)用進展。Nonlinear mixed effect model(NONMEM) has been widely used in estimating population pharmacokinetics parameters of various drugs. 非線性混合效應(yīng)模型法廣泛應(yīng)用于臨床各類藥物的群體藥動學(xué)參數(shù)估算。Nonlinear mixed effect model (NONMEM) 非線性混合效應(yīng)模型法Keywords Nonlinear mixed effect model(NONMEM);Clinical application;Development; 非線性混合效應(yīng)模型法;臨床應(yīng)用;進展;Keywords cyclosporine A;renal transplantation;population pharmacokinetics;NONMEM;Michaelis-Menten model; 環(huán)孢素A;腎移植;群體藥動學(xué);NONMEM;米-曼氏模型;Keywords epilepsy;children;population pharmacokinetics;population pharmacodynamics;valproate;NONMEM software; 癲癇;兒童;丙戊酸鈉;群體藥動學(xué);群體藥效學(xué);NONMEM法; 返回 NONMEM