常見例句DEX is a typical inducer of CYP3A4, by a pregnane X receptor (PXR) mediated mechanism. DEX是典型的CYP3A4誘導劑,其誘導機制由PXR介導。Sequence differences in the ligand binding domain of PXR serve as the molecular basis for the species difference in CYP3A induction. 化學物通過PXR調(diào)節(jié)CYP3A的表達可能是影響化學物體內(nèi)代謝的一條重要途徑。Keywords human PXR;CYP3A4;CYP2B6;luciferase reporter gene;inducer; 熒光素酶報告基因;誘導劑;Parametric X-ray radiation(PXR) 參量X射線輻射 返回 PXR