常見例句Objective: To synthesize bendamustine. 目的:合成鹽酸苯達(dá)莫司汀。Background : Bendamustine, a bifunctional alkylating agent with anticipated purin-like properties is active in metastatic breast cancer (MBC) patients. 苯達(dá)莫司汀,具有烷化劑和嘌呤類似的雙相功能可以在轉(zhuǎn)移性乳腺癌(MBC)患者中發(fā)揮作用。Results: The structure of the target compound was confirmed by MS,1H-NMR,IR analysis.The total yield of bendamustine was 33.5%. 結(jié)果:目標(biāo)化合物的質(zhì)譜、核磁共振氫譜、紅外光譜均與文獻(xiàn)報(bào)道相吻合;總收率為33.;5%25。This multicenter phase II trial defines the toxicity and activity of bendamustine in heavily pretreated patients.Patients and methods: Fifty-one patients were included. 本實(shí)驗(yàn)為多中心II期臨床試驗(yàn),旨在定義苯達(dá)莫司汀在治療失敗乳腺癌患者中的毒性和治療效應(yīng)。Conclusion : Single-agent bendamustine is an active treatment in patients with MBC independent of the previous treatment.The low toxicity profile favors its use as a single agent. 苯達(dá)莫司汀單藥治療MBC具有療效,而其低毒性的特性支持其采用單藥治療。 返回 bendamustine