常見例句And pH gradient active drug loading method was employed to improve the DEE of INT liposome. 通過pH梯度主動載藥法提高脂質(zhì)體的包封率;Thirdly, the drug loading and leasing ratio of P(NIPAm-co-AAm) and PAAc/P(NIPAm-co-AAm) gels was studied. 研究了組分配比對P(NIPAm-co-AAm)和PAAc/P(NIPAm-co-AAm)凝膠的載藥和釋藥率的影響。The entrapment efficiency in cationic liposomes was in the same range even if the drug loading was increased. 即使填充藥量增加,帶有陽離子的脂質(zhì)體的包封率(仍處于相同范圍)沒有變化。All these microspheres showed a restively higher drug loading efficiency at a pH value of about 7. 該制備方法具有一定的普適性,利用該方法可以制備各種無機粒子為核有機聚合物為殼的復(fù)合微球,無機粒子可以是其它金屬(或其合金)或金屬氧化物粒子,通過在其表面覆蓋二氧化硅并進一步用硅烷偶聯(lián)修飾,通過單體的沉淀聚合可以制得復(fù)合微球,殼層聚合物不限于聚(N-異丙基丙烯酰胺),也可以是其它聚合物。Conclusions Docetaxel-NLC with small particle sizes has improved drug loading capacity and controlled drug release properties. 結(jié)論 制備的多西他賽納米脂質(zhì)載體粒徑小,藥物包封率高,并可實現(xiàn)藥物控釋。A high drug loading SLN could be acquired with Compritol 888 ATO as lipid carrier, Soybean lecithin/Pluronic F_(68) (or Soybean lecithin/Tween 80) as emulsifiers. 處方研究表明采用山崳酸甘油酯(Compritol 888 ATO)為脂質(zhì)材料,豆磷脂/PluronicF-68(或豆磷脂/Tween 80)為乳化劑所得SLN載藥量高、穩(wěn)定性好。 返回 Drug-loading